In a large, heavy-bottomed pot (at least 8-quart capacity), add your drained tomatoes, diced bell peppers, diced onions, minced jalapeños, minced garlic, tomato paste, white vinegar, and pickling salt. Add the cumin and red pepper flakes if using.
Stir everything together over medium-high heat. You're looking for the mixture to come to a gentle simmer. Once it begins to bubble, reduce heat to medium and let it simmer for exactly 15 minutes, stirring occasionally. The salsa should reduce slightly and deepen in color. You're not trying to cook it down significantly—you want to maintain the fresh vegetable texture while ensuring everything is heated through and the flavors meld.
Taste and adjust salt if needed. Remember that canned products always taste less seasoned once they cool, so err toward slightly over-seasoned rather than under.